The Louisiana Department of Health has confirmed a fifth death this year caused by Vibrio vulnificus, a dangerous bacterium that can trigger severe infections and, in some cases, death within just a few days. Officials say the state continues to see far more cases than usual and are urging residents to take precautions.
What is the Vibrio bacteria
Vibrio bacteria naturally live in coastal waters, where their numbers climb between May and October as temperatures rise. Infections occur when an open wound is exposed to salt or brackish water, or when someone eats raw or undercooked seafood — particularly oysters. While there are more than a dozen Vibrio species capable of making people sick, Vibrio vulnificus is the most serious. It can lead to gastrointestinal illness, wound infections, or life-threatening blood poisoning. Many patients require intensive care, and some need limb amputations to stop the infection. Roughly one in five people die from it, sometimes within 24 to 48 hours of first becoming ill.
The infection statistics this year
So far in 2025, Louisiana has recorded 26 confirmed infections. All patients required hospitalization, and five have died. Of those cases, about 85% involved wounds exposed to seawater. Nearly all patients — 24 of the 26 — had at least one underlying medical condition. That’s a sharp rise compared with the previous decade, when Louisiana averaged about 10 cases and one death per year.
Nationwide, 150 to 200 Vibrio vulnificus cases are reported annually, with roughly half occurring in Gulf Coast states, including Louisiana, Texas, Mississippi, Alabama, and Florida. Louisiana and Florida historically report the highest numbers of cases and deaths.
Who’s most at risk
Although anyone can contract a Vibrio infection, some people face a much higher risk of severe illness. Conditions that weaken the immune system — such as liver disease, diabetes, cancer, HIV, or thalassemia — make infections more dangerous. Patients who take immune-suppressing therapies or medications that lower stomach acid, as well as those who have had recent stomach surgery, are also more vulnerable.
Vibrio infection signs and symptoms
The illness can present in different ways depending on the route of infection:
- Gastrointestinal infection: watery diarrhea, stomach cramps, nausea, vomiting, fever, and chills.
- Wound infection: fever, redness, swelling, pain, warmth, skin discoloration, or discharge at the site of a cut or scrape.
- Bloodstream infection: fever, chills, dangerously low blood pressure, and blistering skin lesions.
How to protect yourself

Health officials advise avoiding brackish or salt water if you have an open wound, or covering cuts with waterproof bandages if there’s a chance they’ll come into contact with seawater or raw seafood. Wounds exposed to water or seafood should be washed thoroughly with soap and clean water.
People at higher risk should take additional steps, including wearing protective clothing to avoid cuts in the water and gloves when handling raw seafood. Everyone is urged to be careful with shellfish: avoid eating it raw, cook it thoroughly, wash hands after handling, and keep cooked and raw seafood separate to prevent cross-contamination.
The bottom line
Louisiana’s spike in infections is a stark reminder that Vibrio vulnificus is no longer a rare danger. For most people, the risks can be managed with simple precautions. But for those with underlying health issues, even a minor cut or a single raw oyster can have devastating consequences.
As health officials continue to track rising numbers, the message is clear: awareness and prevention are the best defenses against a bacteria that can kill within days.

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